THE HUMAN ENDOCANNABINOID SYSTEM:
Most people don’t know that cannabinoids are already in our bodies. Phytocannabinoids (the cannabinoids in the plant) are simply mimicking endocannabinoids (the cannabinoids that naturally occur in our nervous and immune systems). Our cannabinoid neuronal receptors, first discovered in the 1980’s, are specifically shaped to work with phytocannabinoids. These receptors, named CB1, and CB2, are spread throughout the body, with CB1 receptors concentrated in the brain, and CB2 receptors more prevalent in the immune system.
Our bodies produce two major endocannabinoids: anandamide and 2-arachidonoylglycerol. These compounds activate the endocannabinoid receptors or alternately, block the receptors so other molecules can’t access them for a while. Blocking or activating the receptors modulated neurological and immune functions, and their action signals other biological processes that help maintain bodily homeostatis, otherwise known as balance.
WHAT’S THE BEST WAY TO TAKE CBD?
The most appropriate delivery system for CBD is one that provides an optimal dose for a desired duration with few unwanted side effects. The time of onset and duration of effect vary depending on the method of administration.
There are many delivery methods to include: oral, inhalation, topical, transdermal and ingestion.
CBD-rich oil products can be taken sublingually, orally (as edibles, tinctures, and gel caps), or applied topically. Concentrated CBD oil extracts can also be heated and inhaled with a vape pen. Inhalation is good for treating acute symptoms that require immediate attention; the effects can be felt within a minute or two and typically last for a couple of hours. The effects of orally administered CBD-rich oil can last for four hours or more, but the onset of effects is much slower (30-90 minutes) than inhalation.
Unlike pharmaceutical drugs, which are delivered in specific doses, cannabinoid medicine is highly individualized. This array of options can be exciting and empowering. Educate yourself to understand your options, and to choose the best form and dosage of CBD medicine for yourself.